Lamp2b是什么蛋白
Tīmeklis载体简介 载体序列 LOCUS pcDNA GNSTM-3-RVG-10-Lamp2b-HA 6988 bp ds-DNA circular SYN 06-AUG-2024 DEFINITION Encodes (N to C): GNSTM glycosylation motif, 3 residue spacer, RVG peptide, 10 residue spacer, Lamp2b (exosomal transmembrane protein), 3 residue spacer, HA tag.. ACCESSION . VERSION . Tīmeklis2024. gada 23. jūn. · bamboopiggy. LAMP2基因9号外显子的剪切差异可致所编码的LAMP2蛋白存在LAMP2A、LAMP2B及LAMP2C 3种亚型,区别仅在于溶酶体羧基末端跨膜区域及胞浆短尾。. LAMP2A及LAMP2C在全身各组织中广泛表达,而LAMP2B则选择性地在心肌、骨骼肌及脑组织中高水平表达.
Lamp2b是什么蛋白
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Tīmeklis2024. gada 12. dec. · 但他们没有研究RVG-Lamp2b融合蛋白是否诱导重复给药后的适应性免疫。 事实上,很可能会产生适应性免疫反应。 另一个未被研究者解决的问题是,受阿尔茨海默病影响的大脑中,用于使外泌体靶向大脑的RVG的受体,即α-7-亚基乙酰胆碱受体,明显减少。 这个问题在开发包含抗BACE1 siRNA的RVG-外泌体用于阿尔茨 … Tīmeklis2024. gada 15. nov. · 细胞外小囊泡(sEVsRVG)的脑部神经特异性靶向是通过将sEVs膜蛋白lamp2b和神经靶向性的狂犬病毒糖蛋白衍生肽(RVG)融合递呈在细胞外囊泡上,在细胞及动物水平验证了sEVsRVG-siRNA的抗病毒能力 图3: sEVsRVG-siRNA装载siRNA条件的优化及其在细胞水平上的抗病毒能力 图4:孕鼠模型证明 …
Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and … Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This … Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C … Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid hydrolases that degrade foreign materials and have specialized autolytic functions. These … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an … Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … Skatīt vairāk
Tīmeklis2024. gada 23. maijs · The expression of CTP-Lamp2b peptide on exosomes was stabilized by attaching glycosylation sequences. Exosomes expressing only Lamp2b on exosomal membranes (CTL-Exo) were generated as a control. The in vitro and in vivo uptake of CTL-Exo and CTP-Exo was evaluated in cell lines and mice. Both … TīmeklisLOCUS pcDNA Flag Lamp2b-HA 6880 bp ds-DNA circular SYN 06-AUG-2024 DEFINITION Flag tag with 3 residue spacer fused to the N-terminus of Lamp2b, a transmembrane exosomal protein. 3 residue spacer then HA tag fused to the C-terminus of Lamp2b.. ACCESSION . VERSION . KEYWORDS pcDNA Flag Lamp2b-HA …
Tīmeklis2024. gada 15. okt. · LYSOSOME-ASSOCIATED MEMBRANE PROTEIN 2; LAMP2 Alternative titles; symbols LYSOSOME-ASSOCIATED MEMBRANE PROTEIN B; …
Tīmeklis2024. gada 15. dec. · Abstract. Huntington’s disease is an autosomal-dominant neurodegenerative disease caused by CAG expansion in exon 1 of the huntingtin (HTT) gene.Since mutant huntingtin (mHTT) protein is the root cause of Huntington’s disease, oligonucleotide-based therapeutic approaches using small interfering RNAs … ticket template printable pdfTīmeklis2024. gada 15. okt. · The deduced LAMP2B protein contains 410 amino acids, like the LAMP2A protein, but its C-terminal sequence differs in the last 11 amino acids of the luminal domain, the transmembrane domain, and the cytoplasmic tail. LAMP2B retains the lysosomal targeting signal, gly-tyr-x-x, and has the same number of potential … ticket templates for microsoft wordTīmeklisPlasmid pcDNA GNSTM-3-RVG-10-Lamp2b-HA from Dr. Joshua Leonard's lab contains the insert Lamp2b and is published in J Biol Chem. 2015 Mar 27;290(13):8166-72. doi: 10.1074/jbc.M114.621383. Epub 2015 Feb 5. This plasmid is … ticket templates excelTīmeklisSynthetic peptide corresponding to Human LAMP2B aa 350 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. LAMP2 has 3 distinct isoforms, … ticket template on wordTīmeklis2024. gada 25. marts · In addition, images also showed that LAMP2B colocalization with LAMP2A is lower than expected (73.88 ± 13.09%), indicating that both LAMP2 … ticket templates for freeTīmeklis2024. gada 18. marts · LAMP2B is the predominant isoform expressed in cardiomyocytes. This study evaluates the efficacy of human LAMP2B gene transfer … ticket tennis torinoTīmeklis2024. gada 24. dec. · LAMP-2B is the predominant LAMP-2 isoform expressed in human CMs. ( A) Expression of the three LAMP-2 isoforms in different types of cells was examined by RNA-seq or qPCR. RNAs from three human hearts were used for qPCR. FPKM, fragments per kilobase of exon per million reads. ( B) Immunoblotting … ticketteria caserta